Aguero has scored 116 goals in 176 games for the club, winning two Premier League titles in the process.
He made his professional debut at the age of 15 for Independiente.
In an interview with magazine So Foot, Aguero said: “I have always said that I want to return to Independiente and I will do just that.
“I will return to Independiente when my contract with City expires.
“I do not want to make my comeback when I am too old. If everything goes well, I will return to the club of my heart at the age of 31.”